HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → 5-Chloro-2-(4-fluoro-phenoxy)-3-nitro-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromo-5-chloro-3-nitropyridine | HCID 280681 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Chloro-2-(4-fluoro-phenoxy)-3-nitro-pyridine | HCID 57942410 | — |
Reaction Steps
The title compound was prepared according to general procedure A using 2-bromo-5-chloro-3-nitro-pyridine (750 mg, 3.17 mmol), 4-fluorophenol (463 mmol, 4.13 mmol), K2CO3 (437 mg, 4.75 mmol) and DMF (5 mL). MS m/z: 269.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093247B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-92c9741dc15d4b47975d57f78a59eddd |
| Source note | uspto-grants-2012_01 |