2-Fluoro-6-methoxybenzaldehyde → (3-Amino-5-chloro-pyridin-2-yl)-(2-fluoro-6-methoxy-phenyl)-methanone

HRID 419048노트

반응식

HRID 419048 반응식
[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[C:3]=1[CH:4]=[O:5].[Cl:12][C:13]1[CH:14]=[C:15]([N+:20]([O-])=O)[C:16](I)=[N:17][CH:18]=1>>[NH2:20][C:15]1[C:16]([C:4]([C:3]2[C:6]([O:10][CH3:11])=[CH:7][CH:8]=[CH:9][C:2]=2[F:1])=[O:5])=[N:17][CH:18]=[C:13]([Cl:12])[CH:14]=1

참가 물질

3

반응물 2

HCID 27373572-Fluoro-6-methoxybenzaldehydeHCID 579421085-Chloro-2-iodo-3-nitropyridine

생성물 1

HCID 57942274(3-Amino-5-chloro-pyridin-2-yl)-(2-fluoro-6-methoxy-phenyl)-methanone

실험 절차

(3-Amino-5-chloro-pyridin-2-yl)-(2-fluoro-6-methoxy-phenyl)-methanone was prepared from 2-fluoro-6-methoxybenzaldehyde and 5-chloro-2-iodo-3-nitro-pyridine in three steps according to the General Procedure C. MS m/z: 281.0 (M+Na).

출처 및 근거

ORD 기록
ord-dea81d8459b94727b480e74e9c59e839
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08093247B2

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