HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 5-[3-(2-chloro-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(ethyloxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | 5-(3-(2-chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide | HCID 59452590 | — |
| Product | 5-[3-(2-chloro-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(ethyloxy)benzamide | HCID 59452941 | — |
Reaction Steps
The title compound was prepared in an analogous manner to that described for 5-[3-(2-chloro-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide (Intermediate Example 2) with the following notable exception: ethyl iodide was used instead of methyl iodide in the procedure outlined in step B. MS (M+H, ES+) 506.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093239B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-13f246f442c44d209a6da0b48ea66b77 |
| Source note | uspto-grants-2012_01 |