(2-Methoxypyridin-3-yl)boronic acid → HCID 86632638, compound

HRID 419795Notes

Reaction equation

HRID 419795 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:19]([O:20][C:21](=[O:23])[CH3:22])[C@H:18]([O:24][C:25](=[O:27])[CH3:26])[CH2:17][S:16][C@H:6]1[O:7][C:8]1[C:9]([Cl:15])=[N:10][C:11](I)=[CH:12][CH:13]=1)(=[O:3])[CH3:2].[CH3:28][O:29][C:30]1[C:35](B(O)O)=[CH:34][CH:33]=[CH:32][N:31]=1>>[C:1]([O:4][C@@H:5]1[C@@H:19]([O:20][C:21](=[O:23])[CH3:22])[C@H:18]([O:24][C:25](=[O:27])[CH3:26])[CH2:17][S:16][C@H:6]1[O:7][C:8]1[C:9]([Cl:15])=[N:10][C:11]([C:35]2[C:30]([O:29][CH3:28])=[N:31][CH:32]=[CH:33][CH:34]=2)=[CH:12][CH:13]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 2762709(2-Methoxypyridin-3-yl)boronic acidHCID 86632639HCID 86632639, compound

Product 1

HCID 86632638HCID 86632638, compound

Procedure

By carrying out the operation analogously to example 1, starting from 2-chloro-6-iodo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation X, and 2-methoxy-3-pyridineboronic acid, the desired product is obtained in the form of a pink solid (yield=40%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-42331da1141949e6a88d0e89be9764a3
Source dataset
uspto-grants-2012_01
Patent number
US08093394B2

Reaction notes

Loading…