3-Pyridinylboronic acid → HCID 66651013, compound

HRID 419806Notes

Reaction equation

HRID 419806 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10](Cl)[N:9]=1)(=[O:3])[CH3:2].[N:27]1[CH:32]=[CH:31][CH:30]=[C:29](B(O)O)[CH:28]=1>>[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:29]2[CH:28]=[N:27][CH:32]=[CH:31][CH:30]=2)[N:9]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 86632647HCID 86632647, compound

Product 1

HCID 66651013HCID 66651013, compound

Procedure

By carrying out the operation analogously to example 41, starting from 6-chloro-2-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation XIII, and 3-pyridineboronic acid, the desired product is obtained in the form of a cream powder (yield=38%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-1709c573a3e04d46b1c17ec4f7561a23
Source dataset
uspto-grants-2012_01
Patent number
US08093394B2

Reaction notes

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