Benzo[b]furan-2-boronic acid → HCID 66651208, compound

HRID 419813Notes

Reaction equation

HRID 419813 reaction equation
[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[C:9](Br)=[N:10][CH:11]=[CH:12][CH:13]=1)(=[O:3])[CH3:2].[O:27]1[C:31]2[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=2[CH:29]=[C:28]1B(O)O>>[C:1]([O:4][C@@H:5]1[C@@H:18]([O:19][C:20](=[O:22])[CH3:21])[C@H:17]([O:23][C:24](=[O:26])[CH3:25])[CH2:16][S:15][C@H:6]1[O:7][C:8]1[C:9]([C:28]2[O:27][C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=3[CH:29]=2)=[N:10][CH:11]=[CH:12][CH:13]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 2776266Benzo[b]furan-2-boronic acidHCID 12136256HCID 12136256, compound

Product 1

HCID 66651208HCID 66651208, compound

Procedure

By carrying out the operation analogously to example 1, starting from 2-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation III, and 2-benzofuranboronic acid, the desired product is obtained and is used directly in the deacetylation stage.

Workup

  1. customobtained

Sources & evidence

ORD record
ord-6be42e97598c4529abb3bb41425770b7
Source dataset
uspto-grants-2012_01
Patent number
US08093394B2

Reaction notes

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