HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Fluoropyridin-3-yl)boronic acid → 5-(6-Fluoro-3-pyridinyl)-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Fluoropyridin-3-yl)boronic acid | HCID 2783397 | — |
| Reactant | 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside | HCID 44195502 | — |
| Product | 5-(6-Fluoro-3-pyridinyl)-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside | HCID 66650890 | — |
Reaction Steps
By carrying out the operation analogously to example 1, starting from 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation IX, and 6-fluoro-3-pyridineboronic acid, the desired product is obtained in the form of a cream solid (yield=56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093394B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d0868c5f889e41cfb9ab4e11f8e44c08 |
| Source note | uspto-grants-2012_01 |