HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxypyrimidine-5-boronic acid → 5-(2-Methoxy-5-pyrimidinyl)-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxypyrimidine-5-boronic acid | HCID 2736778 | — |
| Reactant | 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside | HCID 44195502 | — |
| Product | 5-(2-Methoxy-5-pyrimidinyl)-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside | HCID 66650730 | — |
Reaction Steps
By carrying out the operation analogously to example 213, starting from 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation IX, and 2-methoxy-5-pyrimidineboronic acid, the desired product is obtained and is used directly in the deacetylation stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093394B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-9c400869ef6f491dab45de4c9169e98c |
| Source note | uspto-grants-2012_01 |