2-Methylpyridine-4-boronic acid → HCID 66651120, compound

HRID 419828Notes

Reaction equation

HRID 419828 reaction equation
C([O:4][C@@H:5]1[C@@H:18]([O:19]C(=O)C)[C@H:17]([O:23]C(=O)C)[CH2:16][S:15][C@H:6]1[O:7][C:8]1[CH:9]=[N:10][CH:11]=[C:12](Br)[CH:13]=1)(=O)C.[CH3:27][C:28]1[CH:33]=[C:32](B(O)O)[CH:31]=[CH:30][N:29]=1>>[O:7]([C:8]1[CH:9]=[N:10][CH:11]=[C:12]([C:32]2[CH:31]=[CH:30][N:29]=[C:28]([CH3:27])[CH:33]=2)[CH:13]=1)[C@@H:6]1[S:15][CH2:16][C@@H:17]([OH:23])[C@H:18]([OH:19])[C@H:5]1[OH:4]

Participants

3

Reactant 2

HCID 41926642-Methylpyridine-4-boronic acidHCID 441955025-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylo-pyranoside

Product 1

HCID 66651120HCID 66651120, compound

Procedure

By carrying out the operation analogously to example 239, starting from 5-bromo-3-pyridinyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside, obtained according to preparation IX, and 2-methyl-4-pyridineboronic acid, the desired product is obtained in the form of a white solid (yield=28%).

Workup

  1. customobtained

Sources & evidence

ORD record
ord-7586184ae0f74049999e2749f0786175
Source dataset
uspto-grants-2012_01
Patent number
US08093394B2

Reaction notes

Loading…