Bromine → HCID 178526832, compound

HRID 41987Notes

Reaction equation

HRID 41987 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[N:8][CH:9]=1)([O-:3])=[O:2].[Br:11]Br>O>[Br:11][C:6]1[C:7]([OH:10])=[N:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1

Participants

4

Reactant 2

HCID 24408BromineHCID 178526703HCID 178526703, compound

Product 1

HCID 178526832HCID 178526832, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

To a solution of 5-nitropyridin-2-ol (0.06 mol, 8.6 g) in 400 ml of water at 40°, 3.7 ml of Br2 was added. The mixture was stirred at 40° C. for 2.5 h and then it was stirred at room temperature overnight. The solid formed was filtered off, washed with water and dried under vacuum overnight affording 12.5 g (93% of yield) of the expected product.

Workup

  1. stirringit was stirred at room temperature overnight
  2. customThe solid formed
  3. filtrationwas filtered off
  4. washwashed with water
  5. customdried under vacuum overnight
  6. customaffording

Sources & evidence

ORD record
ord-00580a668b3a47f39ddffbe78b38b661
Source dataset
uspto-grants-2013_09
Patent number
US08536165B2

Reaction notes

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