反应详情

5-Methyl-2-(3-nitro-phenyl)-oxazolo[4,5-b]pyridine (50 mg, 0.196 mmol) was mixed with 6 mL of MeOH along with 2 mL of water and 66 mg of sodium hydrosulfide hydrate. The reaction mixture was stirred under reflux for 2 hours. It was then concentrated and extracted with CH2Cl2. The combined organic layers were dried (Na2SO4) and concentrated to afford 20 mg of 3-(5-methyl-oxazolo[4,5-b]pyridin -2-yl)-phenylamine.

1. temperatureunder reflux for 2 hours
2. concentrationIt was then concentrated
3. extractionextracted with CH2Cl2
4. dry with materialThe combined organic layers were dried (Na2SO4)
5. concentrationconcentrated