反应详情

A mixture of 2-(3-methoxyphenyl)-5-nitro-3-phenylpyridine (0.84 mmol, 0.257 g) and Pd/C 10% (0.08 mmol, 0.009 g) in ethanol (5 ml) was stirred for 16 hours under hydrogen atmosphere. The catalyst was filtered off and the solid thoughtfully washed with warm ethanol. The filtrate was evaporated and the crude was purified by chromatography over SiO2 eluting with DCM/methanol mixtures and affording 0.160 g (yield 69%) of the expected product.

1. filtrationThe catalyst was filtered off
2. washthe solid thoughtfully washed with warm ethanol
3. customThe filtrate was evaporated
4. customthe crude was purified by chromatography over SiO2 eluting with DCM/methanol mixtures