1-(2-Amino-4-methoxyphenyl)ethan-1-one → 2'-Amino-3'-methyl-4'-methoxyacetophenone

HRID 420034Notes

Reaction equation

HRID 420034 reaction equation
[CH3:1][O:2][C:3]1[C:4]([CH3:10])=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].NC1C=[C:16]([O:18]C)[CH:15]=CC=1C(=O)C>>[NH2:6][C:5]1[C:4]([CH3:10])=[C:3]([O:2][CH3:1])[CH:9]=[CH:8][C:7]=1[C:16](=[O:18])[CH3:15]

Participants

3

Reactant 2

HCID 106786151-(2-Amino-4-methoxyphenyl)ethan-1-oneHCID 118048223-Methoxy-2-methylaniline

Product 1

HCID 250673162'-Amino-3'-methyl-4'-methoxyacetophenoneYield 23%

Procedure

Compound 40b was synthesized from 3-methoxy-2-methylaniline 39b as a yellow solid in 23% yield, according to the procedure as described for compound 40a.

Sources & evidence

ORD record
ord-3d5fa24a979247b3ad98bdd7048fda9d
Source dataset
uspto-grants-2012_01
Patent number
US08093379B2

Reaction notes

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