HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide | HCID 20773655 | — |
| Reactant | 1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone | HCID 29919988 | — |
| Reactant | 4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride | HCID 57578796 | — |
| Product | N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide | HCID 56605150 | 80% |
Reaction Steps
Compound 42d was synthesized from 1-(2-amino-3-chloro-4-methoxyphenyl)ethanone and compound 38 as a beige solid in 80% yield, according to the procedure as described for compound 42a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093379B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-0cbabe445edc495695d8573dcdae3868 |
| Source note | uspto-grants-2012_01 |