HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide | HCID 20773655 | — |
| Reactant | 4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride | HCID 57578796 | — |
| Reactant | 1-(2-Amino-4-chloro-5-methoxyphenyl)ethanone | HCID 66650482 | — |
| Product | n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide | HCID 66650598 | 69% |
Reaction Steps
Compound 42g was synthesized from compounds 38 and 40g as a beige solid in 69% yield, according to the procedure as described for compound 42a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093379B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-3debd0c5580a4c48b612c783e649703d |
| Source note | uspto-grants-2012_01 |