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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420039Generated: October 29, 2026

N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide

https://huagongshe.com/reaction/420039

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-ThiazolecarboxamideHCID 20773655—
Reactant4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chlorideHCID 57578796—
Reactant1-(2-Amino-4-chloro-5-methoxyphenyl)ethanoneHCID 66650482—
Productn-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamideHCID 6665059869%

Reaction Steps

Compound 42g was synthesized from compounds 38 and 40g as a beige solid in 69% yield, according to the procedure as described for compound 42a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093379B2
Source datasetuspto-grants-2012_01
ORD IDord-3debd0c5580a4c48b612c783e649703d
Source noteuspto-grants-2012_01