HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cesium carbonate → Methyl 2-(6-bromopyridin-3-ylamino)-5-cyclopropylbenzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cesium carbonate | HCID 10796 | — |
| Edukt | 2-Bromo-5-iodopyridine | HCID 4738271 | — |
| Edukt | Methyl 2-amino-5-cyclopropylbenzoate | HCID 13052309 | — |
| Produkt | Methyl 2-(6-bromopyridin-3-ylamino)-5-cyclopropylbenzoate | HCID 86657257 | — |
Reaktionsschritte
Obtained (0.155 g, 43% of yield) following the procedure described in Intermediate 15 starting with methyl 2-amino-5-cyclopropylbenzoate (described in Intermediate 8 (step A)) (1.05 mmol, 0.200 g), 2-bromo-5-iodopyridine (1.05 mmol, 0.297 g) and Cs2CO3 (2.09 mmol, 0.682 g) instead of NaOtBu.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08536165B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-76baa274cfbe43e591e96d19e787b44a |
| Quellennotiz | uspto-grants-2013_09 |