N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-trifluoromethylthiazole-2-carboxamide → 8-Chloro-2-(4-trifluoromethyl-thiazol-2-yl)-7-methoxy-quinolin-4-ol

Participants

Role	Name	HCID	Charge
Reactant	N-(6-acetyl-2-chloro-3-methoxyphenyl)-4-trifluoromethylthiazole-2-carboxamide	HCID 59434824	—
Reactant	HCID 178487691	HCID 178487691	—
Product	8-Chloro-2-(4-trifluoromethyl-thiazol-2-yl)-7-methoxy-quinolin-4-ol	HCID 178487697	70%

Compound 65d was synthesized from compound 64d as a yellow powder in 70% yield, following the procedure as described for compound 43a.