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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420056Generated: October 30, 2026

(2S,4R)-N-(hex-5-enyl)-4-hydroxy-N-methylpyrrolidine-2-carboxamide → (2S,4R)-2-N-(oct-6-enyl)-4-hydroxy-N-methylpyrrolidine-2-carboxamide

https://huagongshe.com/reaction/420056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,4R)-N-(hex-5-enyl)-4-hydroxy-N-methylpyrrolidine-2-carboxamideHCID 57816715—
Reactant(2S,4R)-tert-butyl 2-(N-(oct-6-enyl)-N-methylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylateHCID 66650516—
Product(2S,4R)-2-N-(oct-6-enyl)-4-hydroxy-N-methylpyrrolidine-2-carboxamideHCID 6665073251%

Reaction Steps

Compound 71b was synthesized from compound 70b as yellow oil in 51% yield, following the procedure as described for compound 49.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093379B2
Source datasetuspto-grants-2012_01
ORD IDord-cb382071a55247b2bfe5df5cfe827181
Source noteuspto-grants-2012_01