N-(6-acetyl-2-chloro-3-methoxyphenyl)-5-isopropylisoxazole-3-carboxamide → HCID 178487679, compound

HRID 420069Notes

Reaction equation

HRID 420069 reaction equation
[C:1]([C:4]1[C:9]([NH:10][C:11]([C:13]2[CH:17]=[C:16]([CH:18]([CH3:20])[CH3:19])[O:15][N:14]=2)=O)=[C:8]([Cl:21])[C:7]([O:22][CH3:23])=[CH:6][CH:5]=1)(=[O:3])[CH3:2].C(C1N=C(C2C=C(O)C3C(=CC(OC)=CC=3)N=2)SC=1)(C)C>>[Cl:21][C:8]1[C:7]([O:22][CH3:23])=[CH:6][CH:5]=[C:4]2[C:9]=1[N:10]=[C:11]([C:13]1[CH:17]=[C:16]([CH:18]([CH3:20])[CH3:19])[O:15][N:14]=1)[CH:2]=[C:1]2[OH:3]

Participants

3

Reactant 2

HCID 66650637N-(6-acetyl-2-chloro-3-methoxyphenyl)-5-isopropylisoxazole-3-carboxamideHCID 178487691HCID 178487691, compound

Product 1

HCID 178487679HCID 178487679, compound

Procedure

Compound 93d was synthesized from compound 92d as a white solid in quantitative yield, following the procedure as described for compound 43a.

Sources & evidence

ORD record
ord-8b920cd22f544d20ab3edc584cb814a2
Source dataset
uspto-grants-2012_01
Patent number
US08093379B2

Reaction notes

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