1-Ethynylcyclopropane-1-sulfonamide → (2S,4S)-4-(8-chloro-7-methoxy-2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)quinolin-4-yloxy)-N-(hex-5-enyl)-N-methylpyrrolidine-2-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	1-Ethynylcyclopropane-1-sulfonamide	HCID 57578732	—
Reactant	(2S,4S)-tert-butyl 4-(8-chloro-7-methoxy-2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)quinolin-4-yloxy)-2-(hex-5-enyl(methyl)carbamoyl)pyrrolidine-1-carboxylate	HCID 57816700	—
Product	(2S,4S)-4-(8-chloro-7-methoxy-2-(3-(trifluoromethyl)-1H-pyrazol-1-yl)quinolin-4-yloxy)-N-(hex-5-enyl)-N-methylpyrrolidine-2-carboxamide	HCID 57816693	—

Compound 115 was synthesized from compound 114 as a white solid in quantitative yield, following the procedure as described for compound 82.