1-cyclopropyl-4-methoxy-1H-indole-6-carboxylic acid → 1-cyclopropyl-4-ethoxy-1H-indole-6-carboxylic acid

HRID 420142Notes

Reaction equation

HRID 420142 reaction equation
C1(N2C3C(=C(OC)C=C(C(O)=O)C=3)C=C2)CC1.[CH:18]1([N:21]2[C:29]3[C:24](=[C:25]([O:35][CH2:36][CH3:37])[CH:26]=[C:27]([C:30]([O:32]CC)=[O:31])[CH:28]=3)[CH:23]=[CH:22]2)[CH2:20][CH2:19]1>>[CH:18]1([N:21]2[C:29]3[C:24](=[C:25]([O:35][CH2:36][CH3:37])[CH:26]=[C:27]([C:30]([OH:32])=[O:31])[CH:28]=3)[CH:23]=[CH:22]2)[CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 666494031-cyclopropyl-4-methoxy-1H-indole-6-carboxylic acidHCID 66649415ethyl 1-cyclopropyl-4-ethoxy-1H-indole-6-carboxylate

Product 1

HCID 666493891-cyclopropyl-4-ethoxy-1H-indole-6-carboxylic acid

Procedure

The compound was prepared according to the procedure for 1-Cyclopropyl-4-methoxy-1H-indole-6-carboxylic acid but using ethyl 1-cyclopropyl-4-ethoxy-1H-indole-6-carboxylate in place of ethyl 1-cyclopropyl-4-methoxy-1H-indole-6-carboxylate.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-e6050d6c56f54397b2da6555ea509367
Source dataset
uspto-grants-2012_01
Patent number
US08093389B2

Reaction notes

Loading…