HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-6-chloro-4-picoline → 6-(2-Fluoro-5-methoxyphenyl)-4-methylpyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-6-chloro-4-picoline | HCID 2734425 | — |
| Reactant | 2-Fluoro-5-methoxyphenylboronic acid | HCID 4157211 | — |
| Product | 6-(2-Fluoro-5-methoxyphenyl)-4-methylpyridin-3-amine | HCID 58415871 | 76% |
Reaction Steps
Obtained (1.225 g, yield 76%) following the procedure described in Intermediate 27, starting with 6-chloro-4-methylpyridin-3-amine (7.01 mmol, 1.000 g), 2-fluoro-5-methoxyphenylboronic acid (7.01 mmol, 1.191 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536165B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-1326f287e68d439b9f2ecc60f9cc5155 |
| Source note | uspto-grants-2013_09 |