HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-2-chloropyridine → 6-(2-Fluorophenyl)pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-2-chloropyridine | HCID 79305 | — |
| Reactant | 2-Fluorophenylboronic acid | HCID 2734354 | — |
| Product | 6-(2-Fluorophenyl)pyridin-3-amine | HCID 18955575 | 31% |
Reaction Steps
Obtained (0.210 g, yield 31%) following the procedure described in Intermediate 39, starting with 6-chloropyridin-3-amine (3.50 mmol, 0.45 g), 2-fluorophenylboronic acid (6.94 mmol, 0.97 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536165B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-0c947ad444534faea050dadbc655e2c8 |
| Source note | uspto-grants-2013_09 |