HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl acetate hexane → 3,3-Dimethyl-1,3-dihydroisobenzofuran-5-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | 6-Bromo-1,1-dimethyl-1,3-dihydro-2-benzofuran | HCID 57803842 | — |
| Product | 3,3-Dimethyl-1,3-dihydroisobenzofuran-5-carbaldehyde | HCID 86639542 | — |
Reaction Steps
The title compound is prepared in analogous manner as described for example 47a from 6-bromo-1,1-dimethyl-1,3-dihydro-isobenzofuran to yield a light yellow oil: TLC (hexane-EtOAc 1:1) Rf=0.50; HPLC RtA=1.43 min; 1H NMR (400 MHz, CDCl3): δ10.02 (s, 1H), 7.78 (d, 1H), 7.65 (s, 1H), 7.36 (d, 1H), 5.11 (s, 2H), 1.53 (s, 9H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093406B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-5822a97087434ad0a4e62ec0fb1c5f03 |
| Source note | uspto-grants-2012_01 |