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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42034Generated: October 25, 2026

6-Bromopyridin-3-amine → 6-(2-(Trifluoromethyl)phenyl)pyridin-3-amine

https://huagongshe.com/reaction/42034

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromopyridin-3-amineHCID 642811—
Reactant2-(Trifluoromethyl)benzeneboronic acidHCID 2734387—
Product6-(2-(Trifluoromethyl)phenyl)pyridin-3-amineHCID 6652126359%

Reaction Steps

Obtained (2.05 g, yield 59%) following the procedure described in Intermediate 27, starting with 6-bromopyridin-3-amine, 2-(trifluoromethyl)phenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536165B2
Source datasetuspto-grants-2013_09
ORD IDord-ffd306596ef8463987e9e68d2ef78b8c
Source noteuspto-grants-2013_09