Sodium Hydroxide → HCID 25192469, compound

Participants

Reaction Steps

A similar procedure as described in Example 1, step 3 was used, starting from 4-{3-[6-(3,5-di-pyridin-3-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester (150 mg, 0.26 mmol) and 1.0 N aqueous NaOH (2.5 mL) to afford 4-{2-(2-carboxy-ethyl)-3-[6-(3,5-di-pyridin-3-yl-phenoxy)-hexyl]-phenoxy}-butyric acid (110 mg, 80%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C35H38N2O6 (M+H)+ 583.2803, found 583.2800.

Provenance & Evidence