Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420378Generated: November 1, 2026

Sodium Iodide → HCID 57586567, compound

https://huagongshe.com/reaction/420378

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantChlorotrimethylsilaneHCID 6397—
ReactantHCID 57586542HCID 57586542—
ProductHCID 57586567HCID 5758656798%

Reaction Steps

A similar procedure as described in Example 12, step 6 was used, starting from 3′-fluoro-3-iodo-5-methoxy-biphenyl (1.1 g, 3.35 mmol), sodium iodide (5.024 g, 33.52 mmol), and trimethylsilyl chloride (2.12 mL, 16.76 mmol) to give 3′-fluoro-5-iodo-biphenyl-3-ol (1.03 g, 98%) as an amorphous light brown oil: ES(+)-HRMS m/e calculated for C12H8FIO (M+H)+ 314.9677, found 314.9676.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08093385B2
Source datasetuspto-grants-2012_01
ORD IDord-1f0c2b8c5f9a4a62836fe75c15899e16
Source noteuspto-grants-2012_01