HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 57586567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | HCID 57586542 | HCID 57586542 | — |
| Product | HCID 57586567 | HCID 57586567 | 98% |
Reaction Steps
A similar procedure as described in Example 12, step 6 was used, starting from 3′-fluoro-3-iodo-5-methoxy-biphenyl (1.1 g, 3.35 mmol), sodium iodide (5.024 g, 33.52 mmol), and trimethylsilyl chloride (2.12 mL, 16.76 mmol) to give 3′-fluoro-5-iodo-biphenyl-3-ol (1.03 g, 98%) as an amorphous light brown oil: ES(+)-HRMS m/e calculated for C12H8FIO (M+H)+ 314.9677, found 314.9676.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08093385B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-1f0c2b8c5f9a4a62836fe75c15899e16 |
| Source note | uspto-grants-2012_01 |