4-[3-(6-Bromo-hexyl)-2-(ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester → HCID 57586479, compound

Participants

Reaction Steps

A similar procedure as described in Example 12, step 7 was used, starting from 4-[3-(6-bromo-hexyl)-2-(ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester (1.67 g, 3.54 mmol) and 3′-fluoro-5-iodo-biphenyl-3-ol (1.01 g, 3.22 mmol) to obtain 4-{2-(2-ethoxycarbonyl-ethyl)-3-[6-(3′-fluoro-5-iodo-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid ethyl ester (2.24 g, 99%) as a light yellow oil: ES(+)-HRMS m/e calculated for C35H42FIO6 (M+Na)+ 727.1902, found 727.1902.

Provenance & Evidence