(Pyridin-4-yl)boronic acid → HCID 25191879, compound

Participants

Reaction Steps

A similar procedure as described in Example 5, step 2 was used, starting from 4-{2-(2-carboxy-ethyl)-3-[6-(3′-fluoro-5-iodo-bi phenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid (116 mg, 0.18 mmol) and pyridin-4-ylboronic acid (66 mg, 0.54 mmol) to obtain 4-{2-(2-carboxy-ethyl)-3-[6-(3′-fluoro-5-pyridin-4-yl-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid (28 mg, 26%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C36H38FNO6 (M+H)+ 600.2756, found 600.2754.

Provenance & Evidence