5-Indolylboronic acid → HCID 46888200, compound

Participants

Reaction Steps

A similar procedure as described in Example 5, step 2 was used, starting from 4-{2-(2-carboxy-ethyl)-3-[6-(3′-fluoro-5-iodo-biphenyl-3-yloxy)-hexyl]-phenoxy}-butyric acid (116 mg, 0.18 mmol) and 1H-indol-5-ylboronic acid (66 mg, 0.54 mmol) to obtain 4-(2-(2-carboxy-ethyl)-3-{6-[3′fluoro-5-(1H-indol-5-yl)-biphenyl-3-yloxy]-hexyl}-phenoxy)-butyric acid (35 mg, 31%) as an amorphous light yellow solid: ES(+)-HRMS m/e calculated for C39H40FNO6 (M+Na)+ 660.2732, found 660.2735.

Provenance & Evidence