Sodium Hydroxide → HCID 25192023, compound

Participants

Reaction Steps

A similar procedure as described in Example 12, step 9 was used, starting from 4-{3-[6-(3-benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester (45 mg, 0.12 mmol) and 1.0 N aqueous sodium hydroxide (4 mL) to afford 4-{3-[6-(3-benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy}-butyric acid (22 mg, 54%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C37H39NO8 (M+H)+ 626.2749, found 626.2748.

Provenance & Evidence