Sodium Hydroxide → HCID 67122560, compound

Participants

Reaction Steps

A similar procedure as described in Example 12, step 9 was used, starting from 4-{3-[6-(3-benzo[1,3]dioxol-5-yl-5-pyrimidin-4-yl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy}-butyric acid ethyl ester (26 mg, 0.12 mmol) and 1.0 N aqueous sodium hydroxide (3 mL) to afford 4-{3-[6-(3-benzo[1,3]dioxol-5-yl-5-pyrimidin-4-yl-phenoxy)-hexyl]-2-(2-carboxy-ethyl)-phenoxy}-butyric acid (19 mg, 79%) as an amorphous light yellow solid: ES(+)-HRMS m/e calculated for C36H38N2O8 (M+H)+ 627.2701, found 627.2696.

Provenance & Evidence