Sodium Hydroxide → HCID 86628189, compound

Participants

Reaction Steps

A similar procedure as described in Example 1, step 3 was used, starting from 4-[3-{6-[3-bromo-5-(1,6-dimethyl-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridin-3-yl)-phenoxy]-hexyl}-(2-(2-ethoxycarbonyl-ethyl)-phenoxy)-butyric acid ethyl ester (537 mg, 0.71 mmol) and 1.0 N aqueous sodium hydroxide (7.1 mL) to give 4-[3-{6-[3-bromo-5-(1,6-dimethyl -2-oxo-4-trifluoromethyl-1,2-dihydro-pyridin-3-yl)-phenoxy]-hexyl}-(2-(2-carboxy-ethyl)-phenoxy)-butyric acid (260 mg, 52%) as an amorphous white solid: ES(+)-HRMS m/e calculated for C33H37BrF3NO7 (M+Na)+ 718.1597, found 718.1601.

Provenance & Evidence