(4-Methoxyphenyl)boronic acid → HCID 86628193, compound

Participants

Reaction Steps

A similar procedure as described in Example 1, step 2 was used, starting from 4-[3-{6-[3-bromo-5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl) -phenoxy]-hexyl}-(2-(2-ethoxycarbonyl-ethyl)-phenoxy)-butyric acid ethyl ester (130 mg, 0.18 mmol) and 4-methoxyphenylboronic acid (85 mg, 0.56 mmol) to obtain 4-[3-{6-[5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4′-methoxy-biphenyl-3-yloxy]-hexyl}-(2-(2-ethoxycarbonyl-ethyl)-phenoxy)-butyric acid ethyl ester (59 mg, 44%) as a light yellow oil: ES(+)-HRMS m/e calculated for C42H52N2O9 (M+H)+ 729.3746, found 729.3742.

Provenance & Evidence