Phenylboronic Acid → HCID 86628194, compound

Participants

Reaction Steps

A similar procedure as described in Example 1, step 2 was used, starting from 4-[3-{6-[3-bromo-5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-phenoxy]-hexyl}-(2-(2-ethoxycarbonyl-ethyl)-phenoxy)-butyric acid ethyl ester (27 mg, 0.04 mmol) and phenylboronic acid (23 mg, 0.19 mmol) to obtain 4-[3-{6-[5-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-biphenyl-3-yloxy]-hexyl}-(2-(2-ethoxycarbonyl-ethyl)-phenoxy)-butyric acid ethyl ester (8 mg, 30%) as a light yellow oil: ES(+)-LRMS m/e calculated for C41H50N2O8 (M+H)+ 699.6, found 699.4.

Provenance & Evidence