HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanesulfonyl chloride, 2-methyl- → 8-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanesulfonyl chloride, 2-methyl- | HCID 182236 | — |
| Reactant | 2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione | HCID 58478411 | — |
| Product | 8-(2-Methyl-propane-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione | HCID 53482623 | — |
Reaction Steps
This material was prepared as a white solid in analogy to example 3 from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione, product of example 1 step D), and 2-methyl-propane-1-sulfonyl chloride. MS (ESI): 466.1 (M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097634B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-28e8afab2a8d4b549e2a356ac911ee59 |
| Source note | uspto-grants-2012_01 |