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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420655Generated: October 27, 2026

Methyl iodide → 8-Methyl-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

https://huagongshe.com/reaction/420655

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dioneHCID 58478411—
Product8-Methyl-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dioneHCID 53482682—

Reaction Steps

This material was prepared as a yellow semi-solid in analogy to example 1 step E) from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione and methyl iodide. MS (ESI): 343.1 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097634B2
Source datasetuspto-grants-2012_01
ORD IDord-a1c8f2f1532747939e6efbe6db74c791
Source noteuspto-grants-2012_01