Propane, 1-iodo-2,2-dimethyl- → HCID 53482685, compound

HRID 420658Notes

Reaction equation

HRID 420658 reaction equation
[F:1][C:2]([F:23])([F:22])[O:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:14][CH2:13][C:12]3([CH2:19][CH2:18][NH:17][C:16](=[O:20])[CH2:15]3)[C:11]2=[O:21])=[CH:6][CH:5]=1.[CH2:24](I)[C:25]([CH3:28])([CH3:27])[CH3:26]>>[CH3:24][C:25]([CH3:28])([CH3:27])[CH2:26][N:17]1[CH2:18][CH2:19][C:12]2([C:11](=[O:21])[N:10]([C:7]3[CH:8]=[CH:9][C:4]([O:3][C:2]([F:1])([F:22])[F:23])=[CH:5][CH:6]=3)[CH2:14][CH2:13]2)[CH2:15][C:16]1=[O:20]

Participants

3

Reactant 2

HCID 84953Propane, 1-iodo-2,2-dimethyl-HCID 584784112-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione

Product 1

HCID 53482685HCID 53482685, compound

Procedure

This material was prepared as a off-white semi-solid in analogy to example 1 step E) from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione and neopentyl iodide. MS (ESI): 399.1 (MH+).

Sources & evidence

ORD record
ord-ecf3a470720349c5a2d1abc76615fe70
Source dataset
uspto-grants-2012_01
Patent number
US08097634B2

Reaction notes

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