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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 420660Generated: October 30, 2026

2-Chlorobenzenesulfonyl chloride → 8-(2-Chlorophenylsulfonyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione

https://huagongshe.com/reaction/420660

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chlorobenzenesulfonyl chlorideHCID 76187—
Reactant2-(4-(2,2,2-Trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dioneHCID 58478415—
Product8-(2-Chlorophenylsulfonyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dioneHCID 53482686—

Reaction Steps

This material was prepared as a white solid in analogy to example 3) from 2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione and 2-chlorobenzenesulfonyl chloride. MS (ESI): 501.08 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08097634B2
Source datasetuspto-grants-2012_01
ORD IDord-0385fb6db59e4b9e9047419f985e1c16
Source noteuspto-grants-2012_01