Dichloromethane methanol → HCID 57815447, compound

Participants

Reaction Conditions

Reaction Steps

CrO2 (Magtrieve) (796 mg, 9.48 mmol) was added to a solution of (6-ethyl-5-fluoro-3-pyridinyl)methanol (98 mg, 0.632 mmol) in DCM (5 ml) and the mixture was stirred at 40° C. for 6 h. TLC (10% DCM/MeOH) showed starting material remaining. An excess of CrO2 (Magtrieve) (530 mg, 6.32 mmol) was added. After stirring for 12 h, TLC showed the reaction had been completed. The resulting suspension was filtered and washed with DCM. The filtrate was concentrated under reduced pressure to give 57.4 mg of the title compound as a colourless oil.

Provenance & Evidence