HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5,6-Dimethylpyridin-3-yl)methanol → 5,6-DiMethylnicotinaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5,6-Dimethylpyridin-3-yl)methanol | HCID 46781823 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5,6-DiMethylnicotinaldehyde | HCID 21702824 | 49.3% |
Reaction Steps
To a solution of (5,6-dimethyl-3-pyridinyl)methanol (105 mg, 0.765 mmol) in DCM (4 ml), MnO2 (532 mg, 6.12 mmol) was added. After stirring overnight, an excess of MnO2 (333 mg, 3.83 mmol) was added and then the mixture was stirred for 3 h more. The reaction mixture was filtrated and evaporated to afford 51 mg of title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097628B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-4e447ebbb0e4400d8e9a35070cb277fe |
| Source note | uspto-grants-2012_01 |