Epichlorohydrin → HCID 87093264, compound

HRID 420843Notes

Reaction equation

HRID 420843 reaction equation
[CH2:1]([O:8][C:9]([N:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:17]([CH:19]1[O:21][CH2:20]1)Cl>>[O:21]1[CH2:20][CH:19]1[CH2:17][N:14]1[CH2:15][CH2:16][N:11]([C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[O:10])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 643495Benzyl piperazine-1-carboxylate

Product 1

HCID 87093264HCID 87093264, compound

Procedure

By using 1-benzyloxycarbonylpiperazine (6 ml) and (±)-epichlorohydrin (2.4 ml) as starting materials, the title compound (7.80 g) was obtained in the same manner as that of Reference Example 33.

Sources & evidence

ORD record
ord-00006a017ae1407ca4c43e22ba7e86d8
Source dataset
uspto-grants-2012_01
Patent number
US08097708B2

Reaction notes

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