Ethylenediamine → HCID 66658205, compound

HRID 420857Notes

Reaction equation

HRID 420857 reaction equation
[C:1]([C:4]1[CH:18]=[CH:17][C:7]([O:8][CH2:9][C:10]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:11])=[CH:6][CH:5]=1)(=O)[CH3:2].[CH2:19]([NH2:22])[CH2:20][NH2:21]>C(O)(=O)C>[NH2:21][CH2:20][CH2:19][NH:22][CH:1]([C:4]1[CH:18]=[CH:17][C:7]([O:8][CH2:9][C:10]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:11])=[CH:6][CH:5]=1)[CH3:2]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 39088Acetophenone, 4'-pyrrolidinylcarbonylmethoxy-

Product 1

HCID 66658205HCID 66658205, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

By using 2-(4-acetylphenoxy)-1-(pyrrolidin-1-yl)ethanone (250 mg), ethylenediamine (400 μl) and acetic acid (700 μl) as starting materials, the title compound (163.8 mg) was obtained in the same manner as that of Reference Example 64, (1).

Sources & evidence

ORD record
ord-ec7c6cecf4ef4215b4c6a03a1c24d20e
Source dataset
uspto-grants-2012_01
Patent number
US08097708B2

Reaction notes

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