HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 66658214, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 66657648 | HCID 66657648 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66658214 | HCID 66658214 | — |
Reaction Steps
The title compound was prepared in accordance with step (d) Example 2 from 2-ethoxycarbonylmethyl-1-(4-isopropoxyphenyl)-5-(4-trifluoromethylphenoxy)indole-3-carboxylic acid ethyl ester (265 mg, 0.47 mmol; see step (c) above), NaOH (aq, 2 M, 2.5 mL) and EtOH (15 mL). Yield 176 mg (70%), mp 158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-1f222f928f154eb0855635b939689c11 |
| Source note | uspto-grants-2012_01 |