HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-1,4-benzoquinone → 1-(4-tert-Butylphenyl)-6-chloro-2-ethoxycarbonylmethyl-5-hydroxyindole-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-1,4-benzoquinone | HCID 69671 | — |
| Reactant | 3-(4-tert-Butylphenylamino)pent-2-enedioic acid diethyl ester | HCID 66657741 | — |
| Product | 1-(4-tert-Butylphenyl)-6-chloro-2-ethoxycarbonylmethyl-5-hydroxyindole-3-carboxylic acid ethyl ester | HCID 66657811 | — |
Reaction Steps
The sub-title compound was prepared in accordance with step (b) Example 1 from 3-(4-tert-butylphenylamino)pent-2-enedioic acid diethyl ester (6.2 g, 18.6 mmol, see step (a) above) and 2-chloro-1,4-benzoquinone (3.1 g, 22 mmol). Yield 266 mg (3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-c2db75e89238476397aaff27ed6cf937 |
| Source note | uspto-grants-2012_01 |