HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Chlorophenyl)boronic acid → 5-(3-Chlorophenoxy)-2-ethoxycarbonylmethyl-1-phenylindole-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| Reactant | 2-Ethoxycarbonylmethyl-5-hydroxy-1-phenylindole-3-carboxylic acid ethyl ester | HCID 66657544 | — |
| Product | 5-(3-Chlorophenoxy)-2-ethoxycarbonylmethyl-1-phenylindole-3-carboxylic acid ethyl ester | HCID 66657704 | — |
Reaction Steps
The sub-title compound was prepared in accordance with step (c) Example 1 from 2-ethoxycarbonylmethyl-5-hydroxy-1-phenylindole-3-carboxylic acid ethyl ester (140 mg, 0.38 mmol, see step (b) Example 3) and 3-chlorophenylboronic acid (119 mg, 0.76 mmol). Yield 53 mg (29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-26914294b5ea4404ab8e83f7ee1d6ba3 |
| Source note | uspto-grants-2012_01 |