HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethoxy)phenylboronic acid → HCID 66657661, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethoxy)phenylboronic acid | HCID 2734386 | — |
| Reactant | 1-(4-Dimethylaminophenyl)-2-ethoxycarbonylmethyl-5-hydroxyindole-3-carboxylic acid ethyl ester | HCID 66657692 | — |
| Product | HCID 66657661 | HCID 66657661 | — |
Reaction Steps
The sub-title compound was prepared in accordance with step (c) Example 1 from 1-(4-dimethylaminophenyl)-2-ethoxycarbonylmethyl-5-hydroxyindole-3-carboxylic acid ethyl ester (150 mg, 0.37 mmol, see step (b) Example 16) and 4-trifluoromethoxyphenylboronic acid (50 mg, 0.74 mmol). Yield 120 mg (57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-9e036727898f4479af9e1d73c953ac69 |
| Source note | uspto-grants-2012_01 |