HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 5-bromo-3-formyl-1H-indole-2-carboxylate → 5-Bromo-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 5-bromo-3-formyl-1H-indole-2-carboxylate | HCID 3275613 | — |
| Reactant | 4-Isopropoxybenzeneboronic acid | HCID 3698726 | — |
| Product | 5-Bromo-3-formyl-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester | HCID 57419920 | — |
Reaction Steps
The sub-title compound was prepared in accordance with step (c) Example 1 from 5-bromo-3-formylindole-2-carboxylic acid ethyl ester (4 g, 13.51 mmol; see step (a) above) and 4-isopropoxyphenylboronic acid (4.86 g, 27.02 mmol). Yield 4.1 g (710%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08097623B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-64be0c8f489643f49869c1b0661d63fd |
| Source note | uspto-grants-2012_01 |