Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 10066442, compound

HRID 421023Notes

Reaction equation

HRID 421023 reaction equation
[OH:1][C:2]1[C:3]([C:8]([OH:10])=O)=[N:4][CH:5]=[CH:6][CH:7]=1.[F:11][C:12]([F:25])([F:24])[C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1)[NH2:16]>>[F:11][C:12]([F:24])([F:25])[C:13]1[CH:14]=[C:15]([NH:16][C:8]([C:3]2[C:2]([OH:1])=[CH:7][CH:6]=[CH:5][N:4]=2)=[O:10])[CH:17]=[C:18]([C:20]([F:21])([F:23])[F:22])[CH:19]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 134013-Hydroxypicolinic Acid

Product 1

HCID 10066442HCID 10066442, compoundYield 45%

Procedure

Using 3-hydroxypyridine-2-carboxylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 24 gave the title compound.

Sources & evidence

ORD record
ord-4deca915100a41b0ac55a435493a4982
Source dataset
uspto-grants-2012_01
Patent number
US08097759B2

Reaction notes

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