HCID 67536381, compound → HCID 67535465, compound

Participants

Reaction Steps

The title compound II-ap was prepared in 85% yield from 3,3:17,17-bis(ethylendioxy)-5α-hydroxy-6-methyleneandrostane by the procedure described above for the preparation of 6-methyleneandrostane-3,17-dione (II-ac, Prepn. 13). The combined organic extracts were washed with H2O, dried over Na2SO4 and evaporated to dryness. The residue was purified by flash chromatography (SiO2, n-hexane/AcOEt 60/40). 1H-NMR (300 MHz, DMSO-d6, ppm from TMS): δ 4.91 (1H, s), 4.81 (1H, bs), 4.58 (1H, bs), 2.82 (1H, d), 2.42-1.10 (17H, m), 0.94 (3H, s), 0.77 (3H, s).

Provenance & Evidence